

Health products and supplements are an affordable and effective way to ensure you and your loved ones are getting the daily recommended intake of essential vitamins, minerals and other important nutrients necessary for optimal health.
Berberine 500 delivers 500 mg of berberine HCl (97%) per capsule, derived from non-GMO botanical sources. Berberine supports healthy blood glucose and lipid metabolism within normal limits by activating AMPK, a key enzyme for energy and fat regulation.* Clinical studies have evaluated berberine's effect on healthy glucose balance, triglycerides, cholesterol, and body composition.* Berberine also promotes a balanced gut microbiome, which contributes to gastrointestinal and immune health.* Berberine is well-tolerated and research-supported.*
Supplement Facts
Serving Size: 1 capsule
Servings Per Container: 90
Amount per Serving:
Berberine HCl 97% (from Indian Barberry) (root) (Berberis aristata): 500 mg
Other Ingredients
Hydroxypropyl methylcellulose, microcrystalline cellulose, rice hull concentrate, gum arabic, sunflower oil, silicon dioxide.
As a dietary supplement, take 1 capsule three times daily, or as directed by a healthcare practitioner.
If you are pregnant or lactating, have any health condition or are taking any medication, consult your healthcare practitioner before use.
Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.
• Berberine HCl (97%): A concentrated, plant-derived alkaloid that supports healthy blood glucose and lipid metabolism.*
• AMPK Activation: Berberine activates AMP-activated protein kinase (AMPK), an enzyme that regulates glucose uptake, fat metabolism, and energy balance.*[1]
• Blood Sugar Support: A meta-analysis of 37 studies involving 3,048 participants demonstrated berberine's ability to support glucose regulation without increasing the risk of hypoglycemia.*[2]
• Lipid Metabolism: Berberine has been shown in placebo-controlled trials to support cholesterol and triglyceride balance, promote a healthy HDL to LDL ratio, and enhance lipid oxidation through AMPK activation.*[3,4,7]
• Healthy Weight Management: In a six-month clinical trial, 500 mg twice daily helped maintain healthy weight and cardiometabolic markers in participants with metabolic concerns.*[3]
• Gut Microbiome Balance: Berberine supports a healthy gut microbiota, which contributes to glucose, lipid, and immune system regulation.*[5,6]
• Dosages: In a meta-analysis examining the effects of berberine on metabolic parameters, the most common dosage used across the included studies was 500 mg taken three times daily (1.5 g daily). Other dosing approaches were also represented, including lower daily doses such as 300 mg twice or thrice daily as well as higher doses ranging from 500 mg twice daily up to 1,000 mg three times daily.*[8]
Ideal for individuals seeking support for blood sugar, lipid balance, and gastrointestinal health, particularly those focused on cardiometabolic wellness and gut-immune axis health.*
Each capsule contains 500 mg of berberine HCl (97%), derived from non-GMO sources. Highly concentrated and standardized, this formula reflects clinically relevant dosing used in peer-reviewed studies.*
Berberine HCl 500 mg offers well-documented, multi-system support for those pursuing metabolic balance and digestive health through evidence-based plant-based supplements.*
1. Yin J, et al. Am J Physiol Endocrinol Metab. 2007;294(1):E148–56.
2. Xie W, et al. Front Pharmacol. 2022;13. doi:10.3389/fphar.2022.1015045
3. Derosa G, et al. Expert Opin Biol Ther. 2013;13(4):475–82.
4. Cai Y, et al. Front Pharmacol. 2021;12. doi:10.3389/fphar.2021.631100
5. Zhang L, et al. Front Cell Infect Microbiol. 2021;10. doi:10.3389/fcimb.2020.588517
6. Habtemariam S. Pharmacol Res. 2020;155:104722. doi:10.1016/j.phrs.2020.104722
7. Cai Y, et al. Front Pharmacol. 2023;14. doi:10.3389/fphar.2023.1283784
8. Guo J, et al. Oxid Med Cell Longev. 2021;2021:2074610. doi:10.1155/2021/2074610
Supports glucose metabolism, lipid balance, and gut microbiome health with highly concentrated berberine HCl.*
Our mission is to help you enjoy optimum health through proper nutrition! Good health is all about looking your best and having the energy and stamina to do the things you love. It's difficult to be productive and happy if you're sick or run down all the time. We believe strongly that certain supplements should be at the core of your health program.
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BioHelp is a family owned and operated nutraceutical distribution company. BioHelp offers a wide range of professional only product lines, to everyone who's main goal is to achieve a better quality of life, and we take pride in our ability to educate our clients on product selection. We are your personal concierge to the nutraceutical world. With the growing awareness of food allergies, our staff is able to provide support on products that would best suit the best. Make sure your body is getting all the nutrition it needs to stay healthy and keep you strong. BioHelp will steer you in the right direction and ensure your supplements fit your goals and lifestyle.
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