Other Ingredients

• BioResponse® DIM: A microencapsulated, stable form of diindolylmethane that enhances estrogen detoxification by promoting the formation of beneficial 2-hydroxy estrogen metabolites, while supporting androgen-estrogen balance.* [1,6]
• Vitex agnus-castus Extract: Standardized for key bioactives; supports pituitary gland communication and healthy luteinizing hormone (LH) levels by interacting with dopamine D2 receptors, promoting menstrual cycle regularity and breast comfort.* [14,11]
• Magnesium (as Magnesium Aspartate): Supports systemic magnesium levels, which are important for muscle relaxation, stress modulation, and menstrual cycle comfort.*
• Chromium (as Chromium Picolinate): Provides easily absorbed chromium to meet daily requirements and aid amino acid transport to the brain, supporting mood and metabolic balance.*
• Pyridoxal-5’-Phosphate (P5P): The active form of vitamin B6, supporting neurotransmitter synthesis and enzymatic pathways involved in premenstrual symptom modulation.* [16]

Designed for women seeking comprehensive hormonal detoxification, improved estrogen metabolism, and support for cyclical symptoms associated with the menstrual cycle.*

• Enhanced Bioavailability: Features BioResponse® DIM, shown to be more absorbable and clinically effective than crystalline DIM forms.*
• Clinical Dosing Alignment: Provides DIM and Vitex at levels consistent with those studied in human trials for female hormone and menstrual health support.*
• Full Nutrient Synergy: Includes magnesium, chromium, and P5P to address the nutrient demands involved in hormone balance and neurotransmitter regulation.*

DIM Vitex Hormone Detox delivers an evidence-based, synergistic approach to promote healthy hormone signaling, estrogen metabolism, and cyclical balance for optimal female wellness.*

¹ Thomson CA, et al. Nutr Rev. 2016;74(7):432-43.
² Pondugula SR, et al. Toxicol Lett. 2015;232(3):580-9.
³ Tsuchiya Y, et al. Cancer Lett. 2005;227(2):115-24.
⁴ Thomson CA, et al. Nutr Rev. 2016;74(7):432-43.
⁵ Thomson CA, et al. Breast Cancer Res Treat. 2017;165(1):97-107.
⁶ Sepkovic DW, et al. Cancer Epidemiol Biomarkers Prev. 2009;18(11):2957-64.
⁷ Li Y, et al. Cancer Res. 2010;70(2):646-54.
⁸ Hwang C, et al. Am J Transl Res. 2016;8(1):166-76.
⁹ Anderton MJ, et al. Drug Metab Dispos. 2004;32(6):632-38.
¹⁰ Dalessandri KM, et al. Nutr Cancer. 2004;50(2):161-7.
¹¹ Puglia LT, et al. Front Endocrinol (Lausanne). 2023;14:1269781. doi:10.3389/fendo.2023.1269781
¹² Ooi SL, et al. J Womens Health (Larchmt). 2020;29(2):262-78.
¹³ Csupor D, et al. Complement Ther Med. 2019;47:102190. doi:10.1016/j.ctim.2019.08.024
¹⁴ Franklin M, Odontiadis J. Pharmacopsychiatry. 2003;36(5):176-80.
¹⁵ Wyatt KM, et al. BMJ. 1999;318(7195):1375-81.

Targeted support for female hormone balance, estrogen metabolism, and menstrual cycle health and PMS with clinically studied nutrients and botanicals.*