GABA coFactors IMPROVED

Advanced Amino Acid, Mineral & Herbal Formula for Calming Neurotransmitter Support

With L-Taurine, Valerian, Passionflower & L-Theanine | 90 Vegetarian Capsules

Description

GABA coFactors IMPROVED is a comprehensive formula designed to support the GABAergic system — the brain’s main inhibitory neurotransmitter pathway — by combining amino acids, minerals, and herbal cofactors known to promote calmness, focus, and balanced mood.

This synergistic blend provides targeted nutrients such as vitamin B6 (as pyridoxal-5’-phosphate), zinc, magnesium, and manganese, which are essential for optimal GABA synthesis and receptor function.

It also includes calming amino acids L-taurine and L-theanine, along with standardized herbal extracts of valerian root and passionflower, traditionally used to promote relaxation and restorative sleep.

This formula is particularly beneficial for children with autism spectrum disorder (ASD), ADHD, or anxiety, as these individuals often have imbalances in GABA and glutamate signaling, leading to excitability, sleep disruption, and mood instability.

Key Benefits

• Supports natural GABA production and receptor sensitivity

• Promotes calm focus, emotional balance, and relaxation

• Reduces neuronal excitability and overstimulation

• Enhances stress resilience and supports healthy sleep cycles

• Provides essential cofactors (B6, magnesium, zinc, manganese) for neurotransmitter metabolism

• Helps balance glutamate-GABA ratios in children with autism or ADHD

• Non-sedating, gentle, and safe for long-term use

How It Works

The brain maintains balance through the opposing actions of two major neurotransmitters — glutamate (excitatory) and GABA (inhibitory).

In children with ASD, this balance is often disrupted, with excessive glutamate activity and insufficient GABA function contributing to anxiety, hyperactivity, sleep difficulties, and sensory overload.

GABA coFactors IMPROVED supports this critical balance by:

1. Providing amino acid precursors (taurine, theanine) that enhance GABA activity and neuronal stability.
2. Supplying vitamins and minerals (B6, zinc, magnesium, manganese) required for GABA synthesis and neurotransmitter regulation.
3. Incorporating calming herbal extracts (valerian, passionflower) that naturally modulate GABA receptors and reduce stress-induced excitability.

This multi-pathway approach gently promotes a state of calm focus without sedation or cognitive dulling.

Clinical Relevance for Children with Autism

Children on the autism spectrum frequently exhibit:

• Low GABA levels and impaired inhibitory signaling

• Elevated glutamate, leading to excitotoxicity and agitation

• Nutrient deficiencies (especially vitamin B6, zinc, and magnesium) that impair neurotransmitter metabolism

• Difficulty falling or staying asleep, anxiety, and behavioral rigidity

By addressing these biochemical imbalances, GABA coFactors IMPROVED helps:

• Promote emotional calmness and sensory regulation

• Improve sleep quality and daily focus

• Reduce irritability, anxiety, and hyperactivity

• Support neurotransmitter balance critical for learning and communication

This formula complements therapies targeting nervous system regulation, sleep hygiene, and behavioral stability in children with ASD.

Key Ingredients and Functions

1. Vitamin B6 (as Pyridoxal-5’-Phosphate, 6.8 mg)

The active coenzyme form of vitamin B6 required for the conversion of glutamate to GABA.

• Enhances neurotransmitter synthesis (GABA, serotonin, dopamine)

• Supports mood balance and neurological development

• Highly bioavailable and gentle on the digestive system

2. Magnesium (as Magnesium Succinate, 10 mg)

Essential mineral for neuronal relaxation and NMDA receptor modulation.

• Reduces glutamate excitotoxicity

• Promotes muscle and nervous system calmness

• Supports sleep regulation and stress resilience

3. Zinc (as Zinc Glycinate, 5 mg)

Cofactor for over 300 enzymes, including those involved in neurotransmitter synthesis.

• Modulates GABA receptor sensitivity

• Supports mood stability and reduces irritability

• Commonly deficient in children with ASD and ADHD

4. Manganese (as Manganese Succinate, 10 mg)

Important for enzyme activity and antioxidant defense.

• Supports mitochondrial energy production

• Helps regulate neurotransmitter balance and oxidative stress

5. L-Taurine (150 mg)

A sulfur-containing amino acid that functions as a neuromodulator and GABA receptor agonist.

• Calms neuronal excitability

• Enhances GABAergic transmission

• Supports cell membrane stability and hydration

6. Valerian Root Extract (Valeriana officinalis, 100 mg)

Standardized to 0.8% valerenic acids, known for modulating GABA-A receptors.

• Reduces stress, anxiety, and restlessness

• Promotes relaxation without sedation

• Supports natural sleep onset and quality

7. Passionflower Extract (Passiflora incarnata, 100 mg)

Standardized to 3.5% flavonoids for consistent potency.

• Enhances GABA activity and reduces anxiety

• Supports emotional regulation and better sleep quality

• Traditionally used to calm nervous tension and hyperarousal

8. L-Theanine (15 mg)

A calming amino acid from green tea that promotes alpha brain waves associated with relaxation and focus.

• Reduces stress without sedation

• Enhances GABA, serotonin, and dopamine levels

• Promotes mental clarity and emotional control

9. Lithium (as Lithium Orotate, 10 mg)

A trace mineral in its gentle orotate form that supports mood stability and neuroprotection.

• Promotes calm, balanced emotional states

• Enhances mitochondrial resilience

• Helps regulate mood swings in sensitive individuals

How It Helps Children with Autism

GABA coFactors IMPROVED provides multi-level neurological support for children with ASD by:

• Enhancing GABA synthesis and receptor sensitivity for better calm and focus

• Reducing glutamate excitotoxicity, improving brain balance

• Supporting sleep and behavioral regulation

• Providing essential minerals (Mg, Zn, Mn) that are often depleted

• Helping stabilize mood and emotional responses

Parents and clinicians often report improvements in sleep onset, reduced irritability, better transitions, and overall calmness with consistent use.

Supplement Facts (per 1 capsule)

• Vitamin B6 (as Pyridoxal-5’-Phosphate) — 6.8 mg (400%)

• Magnesium (as Magnesium Succinate) — 10 mg (2%)

• Zinc (as Zinc Glycinate) — 5 mg (45%)

• Manganese (as Manganese Succinate) — 10 mg (435%)

• L-Taurine — 150 mg

• Valerian Root Extract (0.8% Valerenic Acids) — 100 mg

• Passionflower Extract (3.5% Flavonoids) — 100 mg

• L-Theanine — 15 mg

• Lithium (as Lithium Orotate) — 10 mg

Other Ingredients: Vegetarian capsule (hypromellose), cellulose.

Recommended Use

Take 1 capsule 3 times daily, or as directed by your healthcare practitioner.

For children, dosage may be adjusted based on age, weight, and tolerance (e.g., 1–2 capsules daily).

Summary

GABA coFactors IMPROVED offers a targeted, evidence-based blend of nutrients, minerals, and botanicals designed to balance the GABAergic system, support neurotransmitter function, and promote calm, focus, and emotional stability.

It is especially beneficial for:

• Children and adults with autism, ADHD, or anxiety

• Those with GABA-glutamate imbalance or sleep difficulties

• Individuals under chronic stress or with sensory sensitivities

By restoring inhibitory balance in the brain, GABA coFactors IMPROVED supports relaxation, learning, and overall neurological harmony — providing calm without compromise.

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