NEUROinflammation Support

Advanced Phenol-Flavonoid Complex for Brain Immune Modulation and Neuroprotection

With Green Tea, Curcumin, Resveratrol, Baicalin, Apigenin & Luteolin | 90 Vegetarian Capsules

Description

NEUROinflammation Support is a comprehensive phenol-flavonoid formulation designed to promote healthy brain function by supporting microglial balance and reducing oxidative and inflammatory stress in the central nervous system (CNS).

Microglia — the immune cells of the brain — play a crucial role in maintaining the neuronal environment. However, chronic activation of microglia can trigger neuroinflammation, oxidative stress, and neuronal dysfunction. This formula provides a synergistic blend of botanical extracts known to modulate microglial activity, support antioxidant defense, and protect neural tissue.

The formula features catechins, curcuminoids, baicalin, resveratrol, apigenin, luteolin, and rutin, all derived from optimal plant parts (leaf, root, or flower) to maximize efficacy and purity.

This supplement is vegan, gluten-free, and dairy-free, with ingredients validated for potency and purity through third-party testing.

Key Benefits

• Supports healthy microglial activity and brain immune balance

• Promotes antioxidant defense and protection against oxidative stress

• Modulates cytokine signaling and NF-κB activation pathways in neural tissue

• Enhances neuronal communication and synaptic plasticity

• Helps maintain a calm and focused state through neuroinflammatory balance

• Supports mitochondrial protection and cellular energy production

• Free from gluten, dairy, artificial colors, and preservatives

How It Works

Neuroinflammation plays a central role in many neurological and developmental conditions, including autism spectrum disorder (ASD), ADHD, and neurodegenerative diseases. Chronic activation of brain immune cells (microglia) and excess production of inflammatory cytokines can impair synaptic signaling, mitochondrial function, and neurotransmitter balance.

NEUROinflammation Support addresses these processes through a multi-targeted approach:

1. Inhibits microglial overactivation — Reduces pro-inflammatory signaling (NF-κB and COX-2 pathways).
2. Neutralizes oxidative stress — Provides potent antioxidant protection to neuronal cells.
3. Enhances neurogenesis and synaptic plasticity — Promotes learning and brain resilience.
4. Balances cytokine signaling — Modulates immune response without suppressing natural defenses.

Clinical Relevance for Children with Autism (ASD)

Children with ASD often experience neuroinflammation, mitochondrial dysfunction, and oxidative stress — all of which contribute to symptoms such as hyperactivity, sleep disruption, anxiety, and impaired communication.

Studies show that controlling microglial activation and improving antioxidant capacity can reduce irritability, stabilize mood, and support cognitive function in children with autism.

NEUROinflammation Support offers botanical compounds that:

• Downregulate neuroinflammatory mediators (TNF-α, IL-6, IL-1β)

• Reduce oxidative stress by scavenging free radicals and boosting endogenous antioxidants (glutathione, SOD)

• Protect mitochondria and neuronal membranes from damage

• Support calm focus, sensory regulation, and better emotional resilience

This formula is ideal for inclusion in a comprehensive integrative approach to ASD, combining gut-brain balance, mitochondrial support, and neuroprotection.

Key Ingredients and Functions

1. Catechins (from Green Tea Extract, 100 mg)

Powerful antioxidants that help regulate microglial activity and protect neurons from oxidative injury.

• Enhances brain energy metabolism

• Supports cognitive function and learning

• Reduces neuroinflammation and excitotoxicity

2. Curcuminoids (from Turmeric Extract, 100 mg)

Curcumin is a well-known anti-inflammatory and antioxidant compound that modulates inflammatory gene expression.

• Reduces activation of NF-κB and microglia-derived cytokines

• Enhances neuroplasticity and mitochondrial health

• Supports detoxification and blood-brain barrier protection

3. Rutin (from Sophora japonica, 75 mg)

A flavonoid that stabilizes capillaries, improves blood flow, and supports antioxidant recycling.

• Enhances vitamin C function and protects vascular integrity

• Reduces oxidative stress in brain endothelial cells

• Supports anti-inflammatory responses in neural tissue

4. Baicalin (from Baikal Skullcap Root, 60 mg)

A neuroprotective flavone known for its ability to modulate neuroinflammatory pathways.

• Inhibits microglial overactivation and cytokine production

• Enhances GABAergic activity — promoting calmness and focus

• Demonstrated benefits in models of autism and neurodevelopmental disorders

5. Resveratrol (from Japanese Knotweed Root, 50 mg)

A potent activator of SIRT1 and AMPK pathways — crucial for mitochondrial and neuronal health.

• Supports synaptic plasticity and memory formation

• Enhances mitochondrial energy efficiency

• Provides synergistic benefits when combined with curcumin

6. Apigenin (from Chamomile Extract, 30 mg)

A naturally calming flavone that modulates GABA receptors and reduces neuroinflammation.

• Promotes relaxation and stress resilience

• Supports antioxidant defenses in glial cells

• Protects neurons against inflammatory damage

7. Luteolin (from Chrysanthemum Extract, 20 mg)

A highly studied flavonoid known for its strong anti-inflammatory and neuroprotective properties.

• Reduces mast cell and microglial activation — key in ASD-related neuroinflammation

• Protects neurons from oxidative stress and excitotoxicity

• Enhances focus and behavior regulation in children with autism

Synergistic Antioxidant Protection

Together, these flavonoids and polyphenols form a neuroprotective network that modulates immune activity, enhances antioxidant defense, and supports neuronal health.

The synergy between curcumin and resveratrol further enhances SIRT1 activation, mitochondrial support, and gene expression related to inflammation control and longevity.

How It Helps Children with Autism

NEUROinflammation Support addresses several root mechanisms commonly seen in autism:

• Microglial hyperactivity — calms the brain’s immune cells to reduce inflammation

• Oxidative stress — restores antioxidant defenses and reduces free radical damage

• Mitochondrial dysfunction — improves ATP production and neuronal endurance

• Mood and behavior regulation — promotes calmness, emotional balance, and cognitive clarity

This formula complements therapies aimed at improving communication, focus, and sensory integration, making it a valuable part of holistic autism support.

Supplement Facts (per 1 capsule)

• Catechins (Green Tea Extract) — 100 mg

• Curcuminoids (Turmeric Extract) — 100 mg

• Rutin (Sophora japonica) — 75 mg

• Baicalin (Baikal Skullcap Extract) — 60 mg

• Resveratrol (Japanese Knotweed Extract) — 50 mg

• Apigenin (Chamomile Extract) — 30 mg

• Luteolin (Chrysanthemum Extract) — 20 mg

Other Ingredients: Vegetarian capsule (hypromellose), cellulose.

Recommended Use

Take 1 capsule daily, preferably with food, or as directed by your healthcare practitioner.

For children, dosage may be adjusted to ½ capsule daily (contents can be mixed with food or drink).

Summary

NEUROinflammation Support provides a scientifically advanced combination of botanical compounds that target neuroinflammatory pathways, oxidative stress, and microglial overactivity.

It is particularly beneficial for:

• Children with autism or ADHD

• Individuals with neuroinflammation, brain fog, or oxidative stress

• Those seeking natural support for focus, mood, and cognitive health

By calming the brain’s immune system and restoring antioxidant balance, NEUROinflammation Support promotes clearer thinking, better emotional regulation, and overall neurological well-being.