Spectrum B Complex + Benfotiamine

Advanced Activated B-Vitamin Formula for Nervous System, Energy, and Metabolic Health

With Benfotiamine and Quatrefolic® 5-MTHF | 90 Vegetarian Capsules

Description

Spectrum B Complex + Benfotiamine provides a complete and fully activated spectrum of B vitamins essential for neurological function, energy metabolism, cardiovascular health, and cognitive performance.

This advanced formula includes methylated, phosphorylated, and fat-soluble active forms of B vitamins for optimal absorption and bioavailability, including:

• Benfotiamine — a highly bioavailable, fat-soluble form of vitamin B1 (thiamine)
• 5-MTHF (Quatrefolic®) — the most stable and bioactive form of folate
• Methylcobalamin — the coenzyme form of vitamin B12
• Pyridoxal-5’-Phosphate (P-5-P) — the active form of vitamin B6

Unlike conventional B complexes that require metabolic conversion in the liver and intestines, Spectrum B Complex + Benfotiamine delivers vitamins in their pre-activated coenzyme forms, ready for immediate use by the body.

This formula is especially beneficial for children and adults with autism spectrum disorder (ASD), mitochondrial dysfunction, or methylation and detoxification imbalances, which often involve genetic variations such as MTHFR polymorphisms.

Key Benefits

• Provides all essential B vitamins in their bioactive forms for enhanced absorption and cellular utilization

• Supports neurological development, neurotransmitter synthesis, and focus

• Promotes healthy methylation and homocysteine metabolism

• Helps maintain energy production, mitochondrial function, and stress resilience

• Supports carbohydrate metabolism and glucose regulation

• Strengthens cardiovascular health and endothelial integrity

• Aids in maintaining positive mood, mental clarity, and behavioral balance

• Suitable for vegetarians, vegans, and individuals with MTHFR gene variants

How It Works

1. Methylation and Neurotransmitter Support

Methylation is a vital biochemical process for DNA repair, detoxification, and neurotransmitter regulation.

Deficiencies in active forms of folate (5-MTHF), B6, and B12 can impair methylation, leading to mood instability, anxiety, poor focus, and neurological imbalances—symptoms often seen in children with autism.

• 5-MTHF (Quatrefolic®) bypasses the MTHFR enzyme step, directly supporting methylation and neurotransmitter synthesis (serotonin, dopamine, norepinephrine).
• Vitamin B12 (as methylcobalamin) works synergistically with 5-MTHF to convert homocysteine to methionine, supporting brain and cardiovascular health.
• Vitamin B6 (as P-5-P) acts as a cofactor in serotonin, GABA, and dopamine synthesis—critical for emotional regulation and relaxation.

2. Neurological and Mitochondrial Protection

Children on the autism spectrum often exhibit mitochondrial dysfunction and oxidative stress that affect learning, focus, and sensory processing.

The B-vitamin family supports ATP energy production and acts as antioxidants for neural tissue.

• Benfotiamine, a fat-soluble derivative of thiamine (B1), penetrates cell membranes easily, increasing thiamine levels in brain and nerve tissue.
  It activates transketolase, diverting excess glucose metabolism away from harmful pathways that produce advanced glycation end products (AGEs) and oxidative damage.
• By normalizing glucose metabolism and reducing oxidative stress, benfotiamine supports neuronal integrity, eye health, and vascular protection.

3. Energy and Detoxification Support

B vitamins are key cofactors in the Krebs (citric acid) cycle, the body’s main pathway for generating energy (ATP).

They also support phase I and phase II liver detoxification, helping remove metabolic waste and environmental toxins that may worsen behavioral symptoms in children with ASD.

• Riboflavin (B2) and niacin (B3) assist in electron transport and cellular respiration.
• Biotin and pantothenic acid (B5) are essential for fatty acid oxidation and adrenal health, supporting the body’s stress response.
• Choline contributes to acetylcholine synthesis, supporting learning, memory, and healthy methylation.

Why It’s Especially Helpful for Children with Autism

Children with autism often experience:

• Genetic variations (e.g., MTHFR, COMT, CBS) affecting folate metabolism

• Impaired neurotransmitter synthesis (dopamine, serotonin, GABA)

• Mitochondrial dysfunction and oxidative stress

• Low thiamine levels, impacting carbohydrate metabolism and neural energy

Spectrum B Complex + Benfotiamine helps address these challenges by:

• Delivering pre-activated B vitamins that bypass metabolic barriers

• Enhancing neurotransmitter balance to support calmness, focus, and mood stability

• Improving energy and glucose utilization at the cellular level

• Supporting detoxification and antioxidant defenses

• Promoting better cognitive performance, attention, and language development

Key Ingredients and Their Functions

Thiamine (Vitamin B1, as Thiamine HCl) – 20 mg

Essential for energy metabolism and nerve transmission. Supports glucose regulation and brain function.

Benfotiamine – 20 mg

A fat-soluble, highly bioavailable thiamine derivative that protects nerves, eyes, and blood vessels from oxidative and glycation damage. Promotes healthy glucose metabolism and mitochondrial function.

Riboflavin (Vitamin B2, as Riboflavin-5’-Phosphate Sodium) – 20 mg

Supports energy production, detoxification, and antioxidant regeneration.

Niacin (Vitamin B3, as Niacinamide and Niacin) – 140 mg

Promotes energy metabolism, DNA repair, and healthy circulation.

Vitamin B6 (as Pyridoxal-5’-Phosphate) – 20 mg

Active form that supports neurotransmitter synthesis (serotonin, dopamine, GABA) and mood regulation.

Folate (as Quatrefolic® 5-MTHF) – 680 mcg DFE

Methylated folate for optimal methylation, mood balance, and cognitive support.

Vitamin B12 (as Methylcobalamin) – 400 mcg

Active B12 form supporting methylation, myelin integrity, and cognitive health.

Biotin – 400 mcg

Supports fatty acid metabolism, energy production, and neurological health.

Pantothenic Acid (as D-Calcium Pantothenate) – 150 mg

Vital for adrenal hormone production, stress response, and cellular energy.

Choline (as Choline Dihydrogen Citrate) – 30 mg

Essential for acetylcholine production and healthy liver and brain function.

Recommended Use

Take 1 capsule daily, or as directed by your healthcare practitioner.

For children, capsules may be opened and mixed with food or liquid if needed.

Summary

Spectrum B Complex + Benfotiamine is a clinically advanced formula that optimizes B-vitamin absorption and utilization to support:

• Neurotransmitter balance and brain health
• Energy and mitochondrial function
• Detoxification and methylation
• Cognitive clarity and emotional stability

This formula is ideal for children and adults—especially those with autism spectrum disorder, ADHD, chronic fatigue, or metabolic imbalances—who need targeted neurological and cellular support for calm focus, stable mood, and optimal energy production.