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Oxaloacetate (OAA) is a natural compound that plays an essential role in the body’s energy production—especially in the brain. Many neurological disorders, including certain forms of autism, are linked to impaired energy generation in brain cells. These disruptions can affect brain function and lead to developmental challenges or symptoms.

How Oxaloacetate (OAA) Works:

1. Boosts energy levels in brain cells:

• OAA supports ATP (energy) production in brain cells. This is important because low brain energy can lead to neurological issues.

2. Supports mitochondrial function:

• Mitochondria are the “power plants” of cells, generating the energy needed for normal brain function. OAA helps mitochondria work more efficiently, which may benefit children with mitochondrial dysfunction—a common issue in regressive autism.

3. Reduces inflammation:

• OAA decreases inflammation in both the brain and body, which is often a problem in autism. Lowering inflammation supports better brain cell function and overall brain health.

4. Stimulates new brain cell growth:

• OAA promotes neurogenesis, especially in the hippocampus—the area responsible for learning and memory.

5. Balances insulin and lowers blood sugar:

• OAA can help reduce blood glucose and improve insulin signaling, which may enhance brain performance and decrease inflammation.

6. Improves mitochondrial biogenesis:

• OAA activates key pathways that promote the creation of new, healthy mitochondria, leading to improved energy production and overall brain vitality.

Why This Matters in Autism

Children with autism—especially those who experience regression or other neurological challenges—may benefit from OAA because it:

• Improves brain energy supply.

• Reduces inflammation that may hinder brain development.

• Supports overall brain health and function.

Key Points to Note

• Form: OAA is available as a dietary supplement.

• Note: OAA is not a cure for autism but one of several potential therapeutic tools that may help enhance cellular energy and brain health.

Neuroprotective Properties of Oxaloacetic Acid

Oxaloacetate has been shown to powerfully influence two important brain chemicals—GABA and glutamate. Glutamate is an essential neurotransmitter that must remain in delicate balance; when uncontrolled, excess glutamate can overstimulate brain cells, leading to irreversible damage or even cell death.

OAA acts as a glutamate scavenger, removing excess glutamate circulating in the blood and brain. Reducing glutamate levels helps prevent neurodegeneration, giving OAA remarkable neuroprotective properties.

OAA also increases levels of GABA in the brain.

GABA is a calming neurotransmitter that reduces stress and promotes relaxation. This balance between glutamate and GABA contributes to OAA’s mood-enhancing and neuroprotective effects.

benaGene Lozenges contain the same high-quality, heat-stable oxaloacetate formula as benaGene capsules but with faster delivery. Our medical-grade products are safe, non-toxic, and free from keto ingredients, gluten, hormones, or drugs. All products are manufactured in state-of-the-art GMP-certified facilities.

Ingredients:

• 100 mg Oxaloacetate (Anhydrous Enol-Oxaloacetate)

• 150 mg Vitamin C (Ascorbic Acid)

• Vegetarian capsule

• Contains no fillers, binders, dyes, gluten, or preservatives