Product Details

SUPPORTS THE HEALTHY BALANCE OF BACTERIA*

BERBERINE COMPLEX OFFERS TRADITIONAL GASTROINTESTINAL SUPPORT* Berberine Complex is formulated to support the healthy balance of bacteria.* 1 HOW IT WORKS Berberine is a constituent of some plants including Barberry ( Berberis vulgaris ), Oregon Grape ( Berberis aquifolium ), and Goldenseal ( Hydrastis canadensis ). Berberine Complex contains extracts of berberine-containing plants: barberry, Oregon grape, and goldenseal. In addition to berberine, Goldenseal extract also contains other alkaloids such as hydrastine. Traditional use of herbs and extracts often rely on the complex nature of plants rather than isolated bioactive compounds. Berberine Complex is intended for traditional gastrointestinal support.* BERBERINE SUPPORTS HEALTHY BALANCE OF BACTERIA* Goldenseal, which contains alkaloids including berberine, has been traditionally used in North American for gastrointestinal support.* Mechanistic studies in animals and cell culture models suggest berberine may modulate gut microbiota by binding to DNA of bacteria. 1-3 In animal and cell culture studies, berberine has demonstrated an ability to support the intestinal microenvironment.1 In a human Caco-2 cell model, berberine exhibited an ability to maintain tight junctions and support epithelial barrier function. 4 REFERENCES Imenshahidi M et al. Phytother Res. 2016;30:1745-64. Habtemariam S. Pharmacol Res. 2020;155:104722. Tian Y et al. Drug Metab Dispos. 2019;47:86-93. Cao M et al. PLoS ONE. 2013;8(5):e61944.

BERBERINE COMPLEX OFFERS TRADITIONAL GASTROINTESTINAL SUPPORT*

Berberine Complex is formulated to support the healthy balance of bacteria.* 1

HOW IT WORKS

Berberine is a constituent of some plants including Barberry ( Berberis vulgaris ), Oregon Grape ( Berberis aquifolium ), and Goldenseal ( Hydrastis canadensis ). Berberine Complex contains extracts of berberine-containing plants: barberry, Oregon grape, and goldenseal. In addition to berberine, Goldenseal extract also contains other alkaloids such as hydrastine. Traditional use of herbs and extracts often rely on the complex nature of plants rather than isolated bioactive compounds. Berberine Complex is intended for traditional gastrointestinal support.*

BERBERINE SUPPORTS HEALTHY BALANCE OF BACTERIA*

Goldenseal, which contains alkaloids including berberine, has been traditionally used in North American for gastrointestinal support.* Mechanistic studies in animals and cell culture models suggest berberine may modulate gut microbiota by binding to DNA of bacteria. 1-3

In animal and cell culture studies, berberine has demonstrated an ability to support the intestinal microenvironment.1 In a human Caco-2 cell model, berberine exhibited an ability to maintain tight junctions and support epithelial barrier function. 4

REFERENCES

Imenshahidi M et al. Phytother Res. 2016;30:1745-64.

Habtemariam S. Pharmacol Res. 2020;155:104722.

Tian Y et al. Drug Metab Dispos. 2019;47:86-93.

Cao M et al. PLoS ONE. 2013;8(5):e61944.

Ingredients

** Daily Value (DV) not established †Percent daily value is based on a 2000 calorie diet

Other Ingredients plant-derived capsule (hypromellose), cellulose, magnesium stearate, silica

Does Not Contain: Gluten Soy Dairy Colors Artificial Flavors Wheat Preservatives

Directions

Berberine Complex Directions and/or Dosage Adults take 2 capsules three times daily with food, or as recommended by a healthcare professional. Warning Do not use if you are pregnant or nursing. If you have diabetes or if you are taking any medications, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.